pyramid tent features

sharing sensitive in

sharing sensitive information, make sure youre on a federal James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. PubMedGoogle Scholar. IFCC method for alanine aminotransferase (L-alanine: 2-oxoglutarate aminotransferase, EC 2.6.1.2), Bergmeyer HU, Hrder M, Rej R. International Federation of Clinical Chemistry (IFCC) Scientific Committee, Analytical Section: Approved recommendation (1985) on IFCC methods for the measurement of catalytic concentration of enzymes. The mean daily macronutrient and dietary fiber intakes were shown in Table 3. Daily tea drinking is not associated with newly diagnosed non-alcoholic fatty liver disease in Chinese adults: the Tianjin chronic low-grade systemic inflammation and health cohort study. Rezg R, Mornagui B, El-Fazaa S, Gharbi N. Biochemical evaluation of hepatic damage in subchronic exposure to malathion in rats: effect on superoxide dismutase and catalase activities using native PAGE. American DA. PLoS One. PMC legacy view Terms and Conditions, Further studies are warranted to directly assess pesticide levels in tea and confirm the findings of the present study. Moreover, NAFLD is associated with metabolic syndrome [3], type 2 diabetes mellitus [4], and chronic kidney disease [5]. This cross-sectional study aimed to evaluate the associations between tea consumption and the prevalence of newly diagnosed NAFLD among Chinese adults. Among the 19,350 participants, 19.4% were classified as newly diagnosed NAFLD. Med Sci Sports Exerc. Spearmans rank correlation coefficient for energy intake between two food frequency questionnaires administered three months apart was 0.68. According to these results, it can be claimed that GTE prescribed can be considered as an absolute treatment to improve serum levels of Liver enzymes in NAFLD patients. This study was supported by grants from the National Natural Science Foundation of China (No. At the beginning of the study, the groups were similar based upon weight (87.22 11.75 kg and 90.51 14.88 kg in intervention and placebo group, respectively) and liver enzymes. high consumption of red meat [19], fruits [20], sweet products, desserts, and sugar [21]). Yki-Jarvinen H. Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome. 2015;7:477891. [1] This disease may progress to cirrhosis of the liver and hepatocellular carcinoma. Adriano LS, Sampaio HA, Arruda SP, Portela CL, de Melo MLP, Carioca AA, et al. Br J Nutr. Kohgo Y, Ohtake T, Ikuta K, Suzuki Y, Torimoto Y, Kato J. Dysregulation of systemic iron metabolism in alcoholic liver diseases. dissertation which was approved by School of Nutrition and Food Sciences, Isfahan University of Medical Sciences with code 393254. statement and Diagnosis and classification of diabetes mellitus. All the studies pooled in that meta-analysis explored the effect of tea consumption on the risk factors of NAFLD by using green tea extract supplementation as treatment [11]. Part 2. Maturitas. Seppl-Lindroos A, Vehkavaara S, Hkkinen AM, Goto T, Westerbacka J, Sovijrvi A, et al. Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and Fyn. In the present study, the frequency of intake of green tea, oolong tea, and black tea were categorised as: almost never, <1 cup/week, 16 cups/week and1 cup/day. Previous studies have focused on the effect of tea extract on NAFLD. According to the findings of this study, GTE supplementation decrease liver enzymes in patients with NAFLD. Green tea extract protects leptin-deficient, spontaneously obese mice from hepatic steatosis and injury. C R Biol. Targher G, Bertolini L, Padovani R, Rodella S, Zoppini G, Pichiri I, et al. Careers. Saverymuttu SH, Joseph AE, Maxwell JD. Mitochondrial energy metabolism impairment and liver dysfunction following chronic exposure to dichlorvos. Fasting blood sugar level was measured via the glucose oxidase method, triglyceride level was measured via enzymatic methods, and high-density lipoprotein cholesterol level was measured via the chemical precipitation method using reagents obtained from Roche Diagnostics on an automatic biochemistry analyser (Roche Cobas 8000 modular analyser; Roche, Mannheim, Germany). Received 2014 Nov 20; Accepted 2015 Jul 25. The placebo group showed a reduction in ALT and AST levels at the end of the study, but it was no significant. 2014;37(Suppl 1):S8190. Kang JS, Lee WK, Yoon WK, Kim N, Park SK, Park HK, et al. Phytother Res. Part 3. Takato U, Ryuichiro S, Toru N, Takuji T, Michio S. Green tea with high-density catechins improves liver function and fat infiltration in non-alcoholic fatty liver disease (NAFLD) patients. The https:// ensures that you are connecting to the HbA1c separation and quantification were conducted by a high-performance liquid chromatography analyzer (HLC-723G8; Tosoh, Tokyo, Japan). Suzuki Y, Miyoshi N, Isemura M. Health-promoting effects of green tea. Liver ultrasonography was performed by trained sonographers using a TOSHIBA SSA-660A ultrasound machine (Toshiba, Tokyo, Japan) with a 25MHz curved array probe.

2011;343:d3897. Tea in its various processed forms (i.e., non-fermented green tea, partly-fermented oolong tea, and fermented black tea) represents the most widely consumed beverage worldwide [9]. Logistic regression analysis was used to estimate the associations between tea consumption and the prevalence of NAFLD. NAFLD was diagnosed via liver ultrasonography and no history of heavy alcohol intake. Sae-tan S, Grove KA, Lambert JD. If a large quantity of fatty acids continues to be deposited in the liver, accumulation of acylglycerol in the hepatocytes induces oxidative stress that may progress to NAFLD. EGCG, the main catechin in green tea is believed to reduce liver oxidation stress. Management of non-alcoholic fatty liver disease in 2015. The same opaque capsules containing either dried powdered GTE or placebo (cellulose) were administered to the subjects by a research assistant blinded to the contents in the capsules. Angulo P. Obesity and nonalcoholic fatty liver disease. The results are not in line with those of previous studies which found that tea extracts are associated with a lower prevalence of the risk factors of NAFLD. Table 1 shows the components of caffeine and polyphenols in the capsules. Chang Y, Jung HS, Yun KE, Cho J, Cho YK, Ryu S. Cohort study of non-alcoholic fatty liver disease, NAFLD fibrosis score, and the risk of incident diabetes in a Korean population. Metabolic equivalents (METs; hours per week) were calculated using corresponding MET coefficients (3.3, 4.0, and 8.0, respectively) according to the following formula: MET coefficient of activity duration (hours)frequency (days). According to the revised definition and treatment guidelines for NAFLD published by the Chinese Association for the Study of Liver Disease in 2010 [14], we defined heavy drinking as an intake of >140g of alcohol per week among men and>70g per week among women. A controlled study looking at the effects of EGCG on nonheme iron absorption showed that it was decreased by 27% in patients consuming 300 mg EGCG compared with controls consuming placebo. Saadeh S, Younossi ZM, Remer EM, Gramlich T, Ong JP, Hurley M, et al. Int J Epidemiol. ALT and AST were determined by the method developed by International Federation of Clinical Chemistry. All P values for linear trend were calculated according to the categories of tea consumption (almost never: 1, <1 cup/week: 2, 16 cups/week: 3, 1 cup/day: 4) based on logistic regression. Beneficial effects of fermented green tea extract in a rat model of non-alcoholic steatohepatitis. Third, although we considered as many covariates as possible, we cannot rule out the possibility that unmeasured factors might contribute to the associations observed. [13] Experimental evidence supports a role of green tea extract (GTE) or its catechins in protecting against NAFLD by regulating energy homeostasis and decreasing oxidative stress and inflammatory responses. Beneficial effects of tea catechins on diet-induced obesity: Stimulation of lipid catabolism in the liver. The evidence from in vitro and in vivo studies indicates that green tea inhibits dietary lipid absorption [23], decreases lipid accumulation in the liver and adipose tissue [24], improves insulin sensitivity [25], and exerts antioxidant properties [26]. Sociodemographic, behavioural, metabolic, and health status confounding factors were adjusted in logistic regression to explore the associations between daily tea consumption and the prevalence of NAFLD. Associations between tea drinking and the prevalence of newly diagnosed NAFLD were assessed via conditional logistic regression analysis. A total of 32,165 participants without acute inflammatory disease completed a comprehensive health examination and the study questionnaire. However, it is reasonable to exclude participants with cardiovascular disease and cancer when estimating the associations between tea consumption and NAFLD. Green tea group showed significant reductions in ALT and AST levels after 12 weeks period (P < 0.001). Part of Lancet Diabetes Endocrinol. Patients with liver diseases such as Wilson's disease, autoimmune liver disease, hemochromatosis, virus infection, and alcoholic fatty liver as well as those with hepatotoxic, lipid lowering, metformin consumption and antihypertensive medication, contraceptive, and estrogen were excluded. Bellentani S, Dalle Grave R, Suppini A, Marchesini G, Fatty liver Italian N. Behavior therapy for nonalcoholic fatty liver disease: The need for a multidisciplinary approach. Thus, reverse causation was corrected as much as possible. The sample size was computed 35 per group by considering = 0.05 and a power of 90%. [21] In fact, this disease includes a wide range of disorders from accumulated lipid in the big vesicular form to accumulated lipid with inflammation, cirrhosis, and hepatic damage. Increased mRNA expression of acyl-CoA oxidase, one of the peroxisomal -oxidizing enzymes and medium-chain acyl-CoA dehydrogenase, a mitochondrial -oxidizing enzyme, was observed in the liver of the catechin administration group. 2022 BioMed Central Ltd unless otherwise stated. The educational level was assessed by asking the question what is the highest degree you earned? with two possible response categories:

The present study investigated the effects of consumption of green tea in NAFLD patients. In total, 19,350 participants were enrolled in the analyses. Bruno RS, Dugan CE, Smyth JA, DiNatale DA, Koo SI. However, the amounts of catechins in most commercially available green teas is about 60mg per 200ml [28], which is equal to one cup in the present study. 81903302, 91746205, and 81673166), China; China Postdoctoral Science Foundation (No. The correlation coefficients for food items (fruits, vegetables, fish, meat, and beverages) between two food frequency questionnaires administered three months apart ranged from 0.62 to 0.79. To the best of our knowledge, no study has explored the associations between daily tea consumption and the prevalence of NAFLD. 2003;35:1396. Type 2 diabetes was defined as having fasting blood glucose 7.0mmol/, or 2-h postprandial blood glucose 11.1mmol/l, or HbA1c6.5% (48mmol/mol), or a history of diabetes based on the 2014 American Diabetes Association criteria [17]. Also Lifestyles, modifications, particularly weight reduction may more improve the condition of this disease. Kuroda Y, Hara Y. Antimutagenic and anticarcinogenic activity of tea polyphenols. [10,11] In addition, results of animal experiments have indicated that catechins affect the lipid metabolism by decreasing triglyceride and total cholesterol levels[12] and enhancing energy utilization. Yang YX, Wang GY. Wong VW, Wong GL, Choi PC, Chan AW, Li MK, Chan HY, et al. Non-alcoholic fatty liver disease (NAFLD) is rapidly becoming the most common chronic liver disease and potentially affects 25% of the global adult population [1]. [41] Restricting iron absorption through catechins may therefore be effective treatment for NAFLD. Blood pressure was measured twice from the upper left arm using a TM-2655P automatic device (A&D Co., Tokyo, Japan) after five minutes of rest in a seated position. Mutat Res. The results indicated a decrease in weight, after and before the intervention, in both groups. BMI was calculated as weight (kg) divided by height squared (m2), and body fat percentage was estimated with Omron body fat monitor (HBF-306) at baseline and at the end of the study. The placebo group showed a reduction in ALT and AST levels at the end of the study, but it was no significant. Article Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG. There is no significant association between daily tea drinking and newly-diagnosed NAFLD in general Chinese adults. Murase T, Haramizu S, Shimotoyodome A, Tokimitsu I, Hase T. Green tea extract improves running endurance in mice by stimulating lipid utilization during exercise. Blood samples for the analysis of fasting blood glucose and lipid levels were collected in siliconised vacuum plastic tubes. Gastroenterology. There was a significant reduction in carbohydrate intake in green tea group (P = 0.02). Foroughi M, Maghsoudi Z, Ghiasvand R, Iraj B, Askari G. Effect of Vitamin D Supplementation on C-reactive Protein in Patients with Nonalcoholic Fatty Liver. 2016;64:7384. 2018M641753). Privacy [22] In fact, when NAFLD appears that fat comprises 510% of liver's weight. [20] All statistical procedures were performed using SPSS Software (Version 16, Spss Inc. Chicago, IL). Catechins account for ~20% of the flavonoids in green tea leaves. 2007;18:17983. The scores of dietary patterns were used for further analyses as confounding factors. There were no significant differences at baseline between the two groups in terms of age, gender, marital status, education level, physical activity, and the severity of fatty liver. Mechanisms underlying beneficial health effects of tea catechins to improve insulin resistance and endothelial dysfunction. Effect of increased tea consumption on oxidative DNA damage among smokers: A randomized controlled study. Significant increases in serum biochemical indices, including the levels of alanine aminotransferases, aspartate aminotransferase, alkaline phosphatase, total cholesterol, triglycerides, low-density lipoprotein cholesterol, and lipid peroxidation by-products have been observed experimentally after subchronic or chronic exposure to organophosphates [31, 32].

Johansson G, Westerterp KR. Hepatology. Liu et al. This article was extracted from MSc. 2016;115:218995. All subjects were treated in the same fashion. PA in the most recent week was assessed using the short form of the International Physical Activity Questionnaire [15]. A previous study demonstrated that green tea consumption was positively associated with the risk of type 2 diabetes in Chinese adults (hazard ratio: 1.20; 95% CI: 1.14, 1.27) [30]. Mansour-Ghanaei F, Hadi A, Pourmasoumi M, Joukar F, Golpour S, Najafgholizadeh A. Green tea ()-epigallocatechin-3-gallate reduces body weight with regulation of multiple genes expression in adipose tissue of diet-induced obese mice. Further studies are needed to explore the associations between more cups of tea drinking (e.g., equivalent to 500mg of catechins/day) and the prevalence of NAFLD. Catechins are a natural iron chelator and also serve to influence internal absorption of iron. A total of 80 participants (2050 years) with NAFLD were randomly allocated into two groups to receive either green tea extract (GTE) supplement (500 mg GTE tablet per day) or placebo for 90 days. 2011;12:4550. The placebo group showed a reduction in ALT and AST levels at the end of the study, but it was no significant.

Model 1 was adjusted for age, BMI, and sex. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. [36] The difference between the results of Sakata's study and ours study can be because of the GTE dosage during the study.

The mean weight change in the green tea group was significantly greater than the placebo group (P = 0.001). Total PA levels were assessed by combining separate scores for different activities. Data are expressed as mean standard deviation (SD) for normally distributed variables. Non-alcoholic fatty liver disease: an emerging driving force in chronic kidney disease. All participants underwent ultrasonography for determining fatty liver by a single sonographist. Mechanistic insights from computational modeling and the implication for rational design of anti-HIV-1 entry inhibitors? Another strength of the present study is that although a previous study indicated that tea extract supplementation might yield beneficial effects in patients with NAFLD [11], there is limited evidence for the relationship between daily tea consumption and the prevalence of NAFLD in the general population. The FFQ included seven frequency categories ranging from almost never eat to twice or more per day for foods and eight frequency categories ranging from almost never drink to four or more times per day for beverages. Strong association between non alcoholic fatty liver disease (NAFLD) and low 25(OH) vitamin D levels in an adult population with normal serum liver enzymes. [23,24,25] The prevalence of this is 3446% in adults, although the prevalence of it is 21.531.5% in Iran. Changes in biochemical parameters over the study period were estimated by after intervention minus baseline amount was done using paired t-test. Increased hepatocellular mitochondrial -oxidation activity promotes the breakdown of fatty acids and it is thought that it acts as a protective mechanism against NAFLD. J Dig Dis. Powell EE, Cooksley WG, Hanson R, Searle J, Halliday JW, Powell LW. Differences in the mean of the continuous variables between the two groups were tested using analysis of covariance for adjusting for baseline measurements and covariates. 2017;13:297310. It contains high levels of flavonoids, which have antioxidant properties. Healthy dietary pattern is inversely associated with non-alcoholic fatty liver disease in elderly. A previous meta-analysis of four clinical trials suggested that green tea extract supplementation yield benefits on NAFLD related risk factors [11]. Cookies policy. In addition to the development of a fatty liver, NAFLD patients may also exhibit inflammation, necrosis and fibrosis of the liver, which are known as nonalcoholic steatohepatitis (NASH). Employment status was classified as either senior officials and managers or professionals.

Personal characteristics Inc. demographic and disease history were obtained. J Hepatol. Alanine aminotransferase, alkaline phosphatase, aspartate aminotransferase, green tea extract, nonalcoholic fatty liver disease. Hamza A, Zhan CG. Most recently, a meta-analysis that included four randomized controlled trials suggested that there are potential benefits of green tea supplementation on the risk factors of NAFLD [11].

Sitemap 33

sharing sensitive in